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Randal Dull, MD PhD

Biosci Rep. 2018 Nov 23;38(6). pii: BSR20181239. doi: 10.1042/BSR20181239. Print 2018 Dec 21.

Pressure-dependent NOS activation contributes to endothelial hyperpermeability in a model of acute heart failure.

Chignalia AZ1, Isbatan A2, Patel M2, Ripper R2,3, Sharlin J2, Shosfy J2, Borlaug BA4, Dull RO2,5.

Anesth Analg. 2013 Sep;117(3):664-74. doi:10.1213/ANE.0b013e3182975b85.Epub 2013 Jul 8.

Special article: the endothelial glycocalyx: emerging concepts in pulmonary edema and acute lung injury.

Collins SR1, Blank RSDeatherage LSDull RO.


Robert Hahn, MD




Comment: Great coverage of peri-operative fluid management. The best single source of information that any anesthesiologist will find.




Articles by Robert Hahn:

Acta Anaesthesiol Scand. 2019 Nov 18. doi: 10.1111/aas.13511. [Epub ahead of print]

Hypervolemia does not cause degradation of the endothelial glycocalyx layer during open hysterectomy performed under sevoflurane or propofol anesthesia.

Nemme J1, Krizhanovskii C2, Ntika S2, Sabelnikovs O1, Vanags I1, Hahn RG2.


Comment: Very important article; dispels previous reports that suggest hypervolemia results in degradation of the glycocalyx. 


Clin Hemorheol Microcirc. 2019;72(2):161-168. doi: 10.3233/CH-180444.

Biomarkers of endothelial injury in plasma are dependent on kidney function.

Hahn RG1,2, Hasselgren E3, Björne H3, Zdolsek M4, Zdolsek J5.


Comment: excellent investigation demonstrating the crucial role of renal function in plasma concentrations of glycocalyx degradation markers. If your note measuring renal function you can’t conclude that the glycocalyx is breaking down.



Anesth Analg. 2017 Jun;124(6):1824-1833. doi: 10.1213/ANE.0000000000002075.

Arterial Pressure and the Rate of Elimination of Crystalloid Fluid.

Hahn RG1.


Eur J Anaesthesiol. 2016 Jul;33(7):475-82. doi: 10.1097/EJA.0000000000000436.

The half-life of infusion fluids: An educational review.

Hahn RG1, Lyons G.


Branco Furst, MD


Comments: Dr. Furst present a unique view on the role of the heart in the circulatory system. He insights will challenge everything you think you know about how the circulatory system works. These are  “must read” works.




J Cardiothorac Vasc Anesth. 2015 Dec;29(6):1688-701. doi: 10.1053/j.jvca.2015.02.022. Epub 2015 Feb 20.

The Heart: Pressure-Propulsion Pump or Organ of Impedance?

Furst B1.

Adv Physiol Educ. 2016 Jun;40(2):200. doi: 10.1152/advan.00191.2015.

Is the heart a pressure or flow generator? Possible implications and suggestions for cardiovascular pedagogy.

Furst B1, O'Leary AM2


Sheldon Magder, MD


Crit Care. 2016 Sep 10;20:271. doi: 10.1186/s13054-016-1438-7.

Volume and its relationship to cardiac output and venous return.

Magder S1.

Crit Care. 2017 Jan 26;21(1):16. doi: 10.1186/s13054-016-1571-3.

Erratum to: Volume and its relationship to cardiac output and venous return.

Magder S1.


Curr Opin Crit Care. 2015 Oct;21(5):369-75. doi: 10.1097/MCC.0000000000000238.

Understanding central venous pressure: not a preload index?

Magder S1.



Dan Sessler, MD

Br J Anaesth. 2019 May;122(5):563-574. doi: 10.1016/j.bja.2019.01.013. Epub 2019 Feb 27.

Perioperative Quality Initiative consensus statement on intraoperative blood pressure, risk and outcomes for elective surgery.

Sessler DI1, Bloomstone JA2, Aronson S3, Berry C4, Gan TJ5, Kellum JA6, Plumb J7, Mythen MG8, Grocott MPW9, Edwards MR7, Miller TE10; Perioperative Quality Initiative-3 workgroupPOQI chairsMiller TEMythen MGGrocott MPEdwards MRPhysiology groupPreoperative blood pressure groupIntraoperative blood pressure groupPostoperative blood pressure group.

Collaborators (29)

Anesthesiology. 2017 Jun;126(6):995-1004. doi: 10.1097/ALN.0000000000001603.

Lost in Translation: The 2016 John W. Severinghaus Lecture on Translational Research.

Sessler DI1.


Comment: the single moist important summary on the current state of anesthesiology and patient safety.


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